HPLC Whit Automated Mass Spectrometer Detector (LC-MS-MS)

HPLC Whit Automated Mass Spectrometer Detector (LC-MS-MS)  
General Features;
High Resolution Liquid Chromatograph:
Quaternary pump – 1 pc.
Flow: 0.001–5 mL/min, in 1 μL/min increments .
Pressure: 20 - 700 bar with the flow rate up to 5 mL/min .
Serial dual-piston pump
mixing up to 4 solvents at low pressure .
Compressibility Compensation: Fully automated, independent of mobile phase composition
Leak detection included
Vacuum degasser: Built-in, with 4 channels
Flow precision: <0.07% RSD
Flow accuracy: ± 1%
Proportioning precision: <0.15% RSD
Proportioning Accuracy: ±0.5% of full-scale
Autosampler – 1 pc.
Injection volume range: from 0.1 to 100 μl
Precision of injection: <0,25% RSD
Injection volume accuracy: ±0.5%
Pressure range: 20 - 700 bar .
Injection Linearity: r >0.99999
Sample capacity: more than 210 vials of 1,5/2 ml volume
Carry over: 0.003% .
Temperature range: from 4 °C to 40 °C .
Temperature stability: ± 1 °C .
Leak detection
Thermostated column compartment – 1 pc.
Work principle: Still air
Temperature range: from +10 °C to 85 °C .
Temperature stability: ± 0.05 °C .
Temperature accuracy: ±0.5 °C .
Column capacity: 2 columns, up to 300 mm length .
It has leak sensors
DAD detector – 1 pc.
Optical design: 1024 element photodiode array
Light source: Deuterium lamp
Wavelength range: 190-800 nm
Wavelength accuracy: ±1 nm .
Wavelength repeatability: ±0.1 nm .
Number of signals: 8 + 3D .
Scanning rate: 125 Hz
Noise: <±6 μAU .
Drift: <1 mAU/h .
Stainless steel flow cell:  3 μL or less, 12 MPa ., 10 mm optical path length
It has leak sensor
MS/MS detector – 1 pc.
Type of analyzer: triple quadrupole
Mass range: m / z 2 – 3000 (or wider)
Detector type: discrete-dynode detector
Mass resolution: 0.4 Da .
Mass stability: ±0.1 Da in 24h period
Dynamic range: 106 .
Scan speed:  15000 Da / s .
Polarity switching (electronics): ≤ 5 ms including signal stabilization
Vacuum system: turbomolecular pump backed by one mechanical pump
Electrospray ionization (ESI) source
MRM sensitivity S/N ESI positive measured 1 pg of reserpine injected on column, quantifying on the transition m/z 609.3 to 195.1: S/N >1000000:1
MRM sensitivity S/N ESI negative measured 1pg of chloramphenicol injected on column, quantifying on the transition m/z 321.0 to 152.0: S/N >1000000:1
MRM acquisition rate: 600 MRMs/sec
Scan mode: product ion scan, neutral loss scan, precursor ion scan, SIM, MRM
Nitrogen generator – 1 pc.
Nitrogen generator with air compressor capacity of 35 L/min, suitable quality for LCMS application
Computer – 1 pc.
Brand name PC and monitor, Windows 10 (64 bit) appropriate for requested system
The MS control software is a Windows (or equivalent) based platform and have the ability to control both the MS and specified HPLC devices and be compatible with Microsoft Windows 10 (or equivalent)  
Data processing
An application manager for the automated quantification of LC/MS and LC/MS/MS data is supplied.
Data Acquisition, Peak Integration, Calibration, Quantification and QC calculations is fully automated and can be performed in a multiple batch analysis mode.
This software has the ability to simultaneously process quantification data and acquire samples using the same software interface.

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